Sunday, April 12, 2009

Peroxisomal Diseases

Peroxisomes are small round organelles about
0.5–1.0 μm diameter (somewhat smaller than
mitochondria). They are found mainly in the cytoplasm
of kidney and liver cells. They are the
site of some important metabolic functions. The
name is derived fromhydrogen peroxide, which
is formed as an intermediary product of oxidative
metabolism in the peroxisomes. A number
of defects in peroxisome formation or peroxisome
enzymes lead to severe diseases in
humans (peroxisomal diseases).

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